Covid, LP.8.1: the new variant that is alarming the U.S. Cases have quadrupled in three months.

By Elsa Selma Mar 13, 2025

LP.8.1 derives from the JN.1 variant, the strain of the SARS-CoV-2 virus contained in this season’s COVID-19 vaccine. It was first identified in July last year; at the beginning of February, it had been detected in 23 countries. The WHO specifies that there are currently no data on the clinical characteristics of LP.8.1 infection. However, a study published in Lancet Infectious Diseases in mid-February showed that, compared to its “parent variant” JN.1, LP.8.1 has lower infectivity but a higher ability to evade the immune response.

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